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J Parasitol Res. 2014;2014:236838. doi: 10.1155/2014/236838. Epub 2014 Feb 13.

Larvicidal Activity of Cassia occidentalis (Linn.) against the Larvae of Bancroftian Filariasis Vector Mosquito Culex quinquefasciatus.

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Department of Pharmacognosy, Gokula Krishna College of Pharmacy, Nellore District, Sullurpet Andhra Pradesh 524121, India.
Department of Pharma Chemistry, University Institute of Pharmacy, Baba Farid University of Health Sciences, Faridkot, Punjab 151203, India.
Department of Pharmacognosy, Jss College of Pharmacy Rockland, Ooty, Tamil Nadu 643001, India.
National Institute of Communication Diseases Southern India Branch, Coonoor, Tamil Nadu 643101, India.



The plan of this work was to study the larvicidal activity of Cassia occidentalis (Linn.) against the larvae of Culex quinquefasciatus. These larvae are the most significant vectors. They transmit the parasites and pathogens which cause a deadly disease like filariasis, dengue, yellow fever, malaria, Japanese encephalitis, chikungunya, and so forth, which are considered harmful towards the population in tropic and subtropical regions.


The preliminary laboratory trail was undertaken to determine the efficacy of petroleum ether and N-butanol extract of dried whole plant of Cassia occidentalis (Linn.) belonging to the family Caesalpiniaceae at various concentrations against the late third instar larvae of Culex quinquefasciatus by following the WHO guidelines.


The results suggest that 100% mortality effect of petroleum ether and N-butanol extract of Cassia occidentalis (Linn.) was observed at 200 and 300 ppm (parts per million). The results obviously showed use of plants in insect control as an alternative method for minimizing the noxious effect of some pesticide compounds on the environment. Thus the extract of Cassia occidentalis (Linn.) is claimed as more selective and biodegradable agent.


This study justified that plant Cassia occidentalis (Linn.) has a realistic mortality result for larvae of filarial vector. This is safe to individual and communities against mosquitoes. It is a natural weapon for mosquito control.

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