Chromatographic separation of selenium and arsenic: A potential (72)Se/(72)As generator

J Chromatogr A. 2014 May 2:1340:109-14. doi: 10.1016/j.chroma.2014.03.033. Epub 2014 Mar 16.

Abstract

An anion exchange method was developed to separate selenium and arsenic for potential utility in a (72)Se/(72)As generator. The separation of the daughter (72)As from the (72)Se parent is based on the relative acid-base behavior of the two oxo-anions in their highest oxidation states. At pH 1.5, selenate is retained on strongly basic anion exchange resin as HSeO4(-) and SeO4(2-), while neutral arsenic acid, H3AsO4, is eluted.

Keywords: As-72; Ion exchange; Radionuclide generator; Se-72.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anion Exchange Resins
  • Arsenic / analysis
  • Arsenic / chemistry
  • Arsenic / isolation & purification*
  • Chromatography, High Pressure Liquid
  • Chromatography, Ion Exchange / methods*
  • Oxidation-Reduction
  • Radioisotopes / analysis
  • Radioisotopes / chemistry
  • Radioisotopes / isolation & purification*
  • Selenium Radioisotopes / analysis
  • Selenium Radioisotopes / chemistry
  • Selenium Radioisotopes / isolation & purification*

Substances

  • Anion Exchange Resins
  • Radioisotopes
  • Selenium Radioisotopes
  • Arsenic