Format

Send to

Choose Destination
J Nutr Health Aging. 2014 Apr;18(4):441-8. doi: 10.1007/s12603-014-0026-2.

An overview of structure, mechanical properties, and treatment for age-related tendinopathy.

Author information

1
Kanglai Tang, MD/PhD; E-mail: yijian510868@hotmail.com.

Abstract

Tendons transfer tensile loads from muscle to bone, which enable joint motions and stabilize joints. Tendons sustain large mechanical loads in vivo and as a result, tendons were frequently injured. Aging has been confirmed as a predisposing factor of tendinopathy and bad recovery quality following tendon repair. Current treatment methods are generally not effective and involve either symptomatic relief with non-steroidal antiinflammatory drugs and physical therapy or surgery when conservative treatments failed. The limitation in treatment options is due to our incomplete knowledge of age-related tendinopathy. Studies over the past decades have uncovered a number of important mechanical and cellular changes of aging tendon. However, the basis of aging as a major risk factor for tendon injury and impaired tendon healing remained poorly understood. The objectives of this review are to provide an overview of the current knowledge about the aging-associated changes of structure, mechanical properties and treatment in tendon and highlight causes and therapies for age-related tendinopathy.

PMID:
24676328
DOI:
10.1007/s12603-014-0026-2
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center