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Eur J Vasc Endovasc Surg. 2014 Jun;47(6):670-7. doi: 10.1016/j.ejvs.2014.02.015. Epub 2014 Mar 24.

Compression therapy versus surgery in the treatment of patients with varicose veins: A RCT.

Author information

1
Department of Vascular Surgery, Helsinki University Hospital and Institute of Clinical Medicine, Faculty of Medicine, University of Helsinki, Finland.
2
Institute for Health and Welfare, Centre for Health and Social Economics, Helsinki, Finland.
3
Department of Vascular Surgery, Helsinki University Hospital and Institute of Clinical Medicine, Faculty of Medicine, University of Helsinki, Finland; Department of Vascular Surgery, Assiut University Hospitals, Assiut, Egypt.
4
Department of Vascular Surgery, Helsinki University Hospital and Institute of Clinical Medicine, Faculty of Medicine, University of Helsinki, Finland. Electronic address: maarit.venermo@hus.fi.

Abstract

OBJECTIVE:

Superficial venous reflux and varicose veins are common. The aim of this randomized controlled trial was to assess effectiveness of compression therapy compared with surgery for superficial venous reflux.

METHODS:

153 patients with CEAP class C2-C3 and superficial venous reflux were randomized to receive either conservative treatment (compression stockings) (n = 77) or surgery (n = 76). Clinical examination including duplex ultrasound (DUS) was performed at entry and 1 and 2 years after randomization (compression group) or surgery (surgery group). Venous Clinical Severity Score without compression stockings (VCSS-S), Venous Segmental Disease Score (VSDS), Venous Disability Score (VDS), and health-related quality of life (HRQoL) were assessed at entry and at the follow-ups. Data were analysed on an intention-to-treat basis and according to the actual treatment performed.

RESULTS:

At 2 years, 70/76 patients in the surgery group and 11/77 patients in the compression group had been operated on. VCSS-S decreased from 4.6 to 3.5 in the compression group (p < .01) and from 4.8 to 0.6 in the surgery group (p < .001). VSDS decreased from 7.7 to 7.0 in the compression group and from 8.2 to 0.9 in the surgery group (p < .0001). HRQoL did not change in the compression group, but improved significantly in the surgery group.

CONCLUSION:

The surgical elimination of non-complicated superficial venous reflux is an effective treatment when compared with providing compression stockings only.

KEYWORDS:

Compression therapy; Operative treatment; Superficial venous reflux; Varicose veins

PMID:
24675145
DOI:
10.1016/j.ejvs.2014.02.015
[Indexed for MEDLINE]
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