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Gastroenterol Hepatol (N Y). 2012 Nov;8(11):739-45.

Low-FODMAP Diet for Treatment of Irritable Bowel Syndrome.

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Dr. Magge is a Fellow and Dr. Lembo is an Associate Professor of Medicine in the Division of Gastroenterology at Beth Israel Deaconess Medical Center in Boston, Massachusetts.


Functional bowel disorders, including irritable bowel syndrome (IBS), are common disorders that have a significant impact on patients' quality of life. These disorders present major challenges to healthcare providers, as few effective medical therapies are currently available. Recently, there has been increasing interest in dietary therapies for IBS, particularly a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs). Since ingestion of FODMAPs increases the delivery of readily fermentable substrates and water to the distal small intestine and colon-which results in luminal distention and gas-the reduction of FODMAPs in a patient's diet may improve functional gastrointestinal symptoms. This paper will review the pathophysiology of IBS and the role of FODMAPs for the treatment of this condition.


FODMAPs; Irritable bowel syndrome; food allergy; food intolerance; hydrogen breath testing; small intestinal bacterial overgrowth


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