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JAAPA. 2014 Apr;27(4):36-44. doi: 10.1097/01.JAA.0000442702.95598.fc.

Diamond-Blackfan anemia and nutritional deficiency-induced anemia in children.

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David Gelbart is a physician assistant at Advanced Care Emergency Services at Western Arizona Regional Medical Center in Bullhead City, Ariz. The author has disclosed no potential conflicts of interest, financial or otherwise.


Diamond-Blackfan anemia is a rare, inherited disease that characteristically presents as a chronic, normochromic macrocytosis due to red cell lineage bone marrow failure. Although studies are elaborating on the genetic basis for its associated comorbidities, little has been published comparing this anemia to other chronic anemias that have similar laboratory results in children. This article offers a global perspective of the disease and compares it with anemia due to vitamin B12 and folate deficiency in children.

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