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Diabetes Metab Syndr. 2014 Jan-Mar;8(1):57-61. doi: 10.1016/j.dsx.2013.10.004. Epub 2013 Nov 15.

An integrated medical treatment for type-2 diabetes.

Author information

1
Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy. Electronic address: velio.bocci@unisi.it.
2
Department of Internal Medicine, Division of Endocrinology, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands.
3
Department of Physiology, University of Siena, Siena, Italy.
4
Department of Internal Medicine, Division of Endocrinology, Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands. Electronic address: valter.travagli@unisi.it.

Abstract

This paper tries to emphasize two relevant concepts: the first is that type 2 diabetes is a chronic diseases characterized by both a dysmetabolism and a chronic oxidative stress. A variety of orthodox drugs are somewhat able to correct the metabolic alterations, but do not deal with the chronic inflammation. Consequently, as the validity of precisely treating blood with therapeutic ozone concentrations in restoring a redox homeostasis has been now demonstrated, the integration of ozone therapy appears essential for a rational treatment of type 2 diabetes. Such a combination may be able to reduce the diabetic epidemic.

KEYWORDS:

Antioxidants; Diabetes; Nrf2 activation; Oxidative stress; Oxygen-ozonetherapy

PMID:
24661761
DOI:
10.1016/j.dsx.2013.10.004
[Indexed for MEDLINE]

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