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Dent Clin North Am. 2014 Apr;58(2):299-313. doi: 10.1016/j.cden.2014.01.001.

Oral lichen planus and lichenoid mucositis.

Author information

1
Department of Oral Health and Diagnostic Sciences, College of Dental Medicine, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA; Department of Otolaryngology/Head & Neck Surgery, Medical College of Georgia, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA; Department of Dermatology, Medical College of Georgia, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA. Electronic address: SDEROSSI@gru.edu.
2
Department of Oral Rehabilitation, College of Dental Medicine, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA.

Abstract

Oral lichen planus (OLP) is commonly found in middle-aged women. Although the cause is unknown, research points to several complex immunologic events and cells that are responsible for the inflammatory destruction and chronicity of these lesions. Biopsy for histologic diagnosis is recommended. The mainstay of treatment remains topical corticosteroids; however, newer therapies such as immunomodulating agents are available for recalcitrant lesions. In cases of lichenoid mucositis or reactions, treatment should be directed at identifying and removing the presumed cause. Given the apparent risk of squamous cell carcinoma in these patients, frequent follow-up and repeat biopsy are vital.

KEYWORDS:

Lichen planus; Lichenoid drug reaction; Lichenoid mucositis; Oral lichen planus

PMID:
24655524
DOI:
10.1016/j.cden.2014.01.001
[Indexed for MEDLINE]
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