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Afr J Tradit Complement Altern Med. 2013 Nov 2;11(1):97-102. eCollection 2014.

Study on anti-atherosclerotic effect of Suxiao Jiuxin Pill and its mechanism.

Author information

1
The Military General Hospital of BeiJing PLASurgical Dept Vascular Diseases, Beijing, China.

Abstract

BACKGROUND:

Suxiao Jiuxin Pill is composed of Ligusticum wallichii, Borneolum Syntheticum and other drugs; it has qi promoting and blood circulation activating, meridian dredging and pain relieving efficacies. The objective of this paper is to study the effect of Suxiao Jiuxin Pill (quick-acting heart reliever), in atherosclerosis (AS) rat model and explore the mechanism for its prevention and treatment of AS.

MATERIALS AND METHODS:

AS rat model was established by high cholesterol diet and single intra-peritoneal injection of increased dose of vitamin D3.

RESULTS:

Compared with the model group, Suxiao Jiuxin Pill medium-and high-dose groups and atorvastatin group can effectively regulate lipid metabolism.

CONCLUSION:

We conclude that Suxiao Jiuxin Pill has a good hypo-lipidemic effect, and can inhibit the occurrence and development of AS.

KEYWORDS:

Suxiao Jiuxin Pill; atherosclerosis; atorvastatin

PMID:
24653560
PMCID:
PMC3957248
[Indexed for MEDLINE]
Free PMC Article
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