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J Comput Assist Tomogr. 2014 May-Jun;38(3):444-50. doi: 10.1097/RCT.0000000000000044.

Image quality with single-heartbeat 320-multidetector computed tomographic coronary angiography.

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  • 1From the *University of Edinburgh/British Heart Foundation Centre for Cardiovascular Science, †Clinical Research Imaging Centre, University of Edinburgh; and ‡Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.



We aimed to establish the feasibility of single-heartbeat 320-multidetector computed tomographic coronary angiography (CTCA) and assess variables affecting image quality.


Consecutive patients (n = 249, 38% male) underwent CTCA. Two observers assessed image quality using a 4-point scale (1, excellent; 4, poor).


Mean heart rate was 60 beats per minute (95% confidence interval, 59-62); body mass index, 29 kg/m (28-30); and dose-length product, 283 mGy·cm (266-301). During scanning, 133 (51%) received sublingual glyceryl trinitrate (GTN), 9 (4%) had ectopics, and 12 (5%) had atrial fibrillation. Diagnostic image quality was obtained in 99% with mean image quality of 1.4 (1.3, 1.5). Age, sex, atrial fibrillation, ectopics, diabetes mellitus (12%), and obstructive disease were not related to image quality. A lower heart rate and GTN were associated with improved image quality (P ≤ 0.001).


Optimal image quality in single-heartbeat 320-multidetector CTCA is achievable in 99% of unselected patients. Image quality is improved by lower heart rate and GTN.

[PubMed - indexed for MEDLINE]
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