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Cardiovasc Diagn Ther. 2014 Feb;4(1):21-7. doi: 10.3978/j.issn.2223-3652.2014.02.05.

Utility of balloon assisted technique in trans catheter closure of very large (≥35 mm) atrial septal defects.

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1
Department of Cardiology, Jawaharlal Institute of Post graduate Medical Education and Research, Pondicherry, India.

Abstract

BACKGROUND:

Very few published data is available on the outcomes of balloon assisted techniques (BATs) for trans catheter closure (TCC) of very large (Defined as ≥35 mm size) ostium secundum atrial septal defect (ASD).

OBJECTIVE:

To study the utility of BAT as against conventional techniques (CT) in TCC of very large ostium secundum ASD (≥35 mm) over the past 5-year period and to find out the association of different morphological features of the defects in relation to TCC outcomes.

STUDY DESIGN AND METHODS:

Descriptive single center retrospective study of patients with very large ostium secundum ASD (≥35 mm size) who were subjected to TCC.

RESULTS:

Thirty-three out of 36 patients with ≥35 mm ASD and complex morphological features underwent successful TCC. The study patients had high prevalence of absent aortic and posterior rims with posterior mal-alignment of the septum. BAT was successful in 28/31 (90.3%) patients while CT had a success rate of 16%. The mean trans-esophageal echocardiography (TEE) ASD size with BAT success 37 (SD 1.3) mm and CT failure 36.2 (SD 1.1) mm was not different (P=0.06). On univariate analysis of different morphological features, posterior mal alignment of the septum was associated failure of CT (P=0.01). There was no urgent referral for surgery and patients did well on follow up.

CONCLUSIONS:

Balloon assisted device closure of (≥35 mm) ASD had 90% success rate. BAT helps in controlled delivery and device alignment in very large ASD with posterior malalignment of the septum and is often helpful when CT fails.

KEYWORDS:

Very large atrial septal defect (very large ASD); balloon assisted technique (BAT); malaligned septum

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