[The taxonomy of the Issyk-Kul virus (ISKV, Bunyaviridae, Nairovirus), the etiologic agent of the Issyk-Kul fever isolated from bats (Vespertilionidae) and ticks Argas (Carios) vespertilionis (Latreille, 1796)]

Vopr Virusol. 2013 Sep-Oct;58(5):11-5.
[Article in Russian]

Abstract

The Issyk-Kul virus (etiological agent of the Issyk-Kul fever) was originally isolated from bats (Nyctalus noctula Schreber, 1774 (Chiroptera: Vespertilionidae)) and their parasites ticks (Argas (Carios) vespertilionis Latreille, 1796 (Parasitiformes: Argasidae)) in Kirghizia. Sporadic cases and epidemics of the Issyk-Kul fever are observed in Central Asia since 1979. The ISKV genome was de novo sequenced using the next-generation sequencing technology. According to the molecular-genetic and phylogenetic analysis, the ISKV is a member of a novel group in the genus Nairovirus (Bunyaviridae). Based on the data obtained, molecular-genetic methods can be used for ISKV detection (PCR) for the Issyk-Kul fever monitoring and diagnosis in the endemic areas.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Argas / virology*
  • Brain / virology
  • Bunyaviridae Infections / epidemiology
  • Bunyaviridae Infections / veterinary*
  • Bunyaviridae Infections / virology
  • Chiroptera / virology*
  • Genomic Library
  • Kyrgyzstan / epidemiology
  • Nairovirus / classification*
  • Nairovirus / genetics
  • Nairovirus / isolation & purification
  • Phylogeny*
  • Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid