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Ann Oncol. 2014 Jul;25(7):1270-83. doi: 10.1093/annonc/mdu022. Epub 2014 Mar 16.

Management of elderly patients with NSCLC; updated expert's opinion paper: EORTC Elderly Task Force, Lung Cancer Group and International Society for Geriatric Oncology.

Author information

1
Medical Department, European Organization for Research and Treatment of Cancer, Brussels, Belgium athanasios.pallis@eortc.be athanasios.g.pallis@gsk.com.
2
Division of Medical Oncology, 'S.G. Moscati' Hospital-Avellino, Avellino, Italy.
3
Department of Internal Medicine II, Jena University Hospital, Jena, Germany.
4
The Christie NHS Foundation Trust, Manchester, UK.
5
Lung Cancer Early Detection Unit, Division of Thoracic Surgery, European Institute of Oncology, Milano, Italy.
6
Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
7
Department of Medical Oncology, S. Paolo Hospital, Milan, Italy.
8
The Royal Marsden NHS Foundation, Surrey, UK.

Abstract

Non-small-cell lung cancer (NSCLC) is a very common disease in the elderly population and its incidence in this particular population is expected to increase further, because of the ageing of the Western population. Despite this, limited data are available for the treatment of these patients and, therefore, the development of evidence-based treatment recommendations is challenging. In 2010, European Organization for Research and Treatment of Cancer (EORTC) took an initiative in collaboration with International Society of Geriatric Oncology (SIOG) and created an experts panel that provided an experts' opinion consensus paper for the management of elderly NSCLC patients. Since this publication, important new data are available and EORTC and SIOG recommended to update the 2010 recommendations. Besides recommendations for surgery, adjuvant chemotherapy and radiotherapy, treatment of locally advanced and metastatic disease, recommendations were expanded, to include data on patient preferences and geriatric assessment.

KEYWORDS:

EORTC; NSCLC; SIOG; age; elderly

PMID:
24638905
DOI:
10.1093/annonc/mdu022
[Indexed for MEDLINE]

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