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Arq Neuropsiquiatr. 2014 Jan;72(1):38-43. doi: 10.1590/0004-282X20130195.

A short neuropsychological evaluation of patients with primary Sjögren's syndrome.

Author information

1
Universidade Federal do Estado do Rio de Janeiro, Rio de JaneiroRJ, Brazil.
2
Serviço de Reumatologia, Hospital Universitário Gaffréé e Guinle, UNIRIO, Rio de JaneiroRJ, Brazil.
3
Universidade Católica Rio de Janeiro, Rio de JaneiroRJ, Brazil.
4
a, a, Universidade Federal do Estado do Rio de Janeiro, Rio de JaneiroRJ, Brazil.

Abstract

OBJECTIVE:

To investigate cognitive deficits in patients with primary Sjögren's syndrome (PSS).

METHOD:

Eighteen patients with PSS, aged between 25 and 61 years, were subjected to a short neuropsychological battery and compared with 18 patients with multiple sclerosis and 18 healthy controls.

RESULTS:

The analysis of variance (ANOVA) revealed that the clinical groups had significantly worse performance than the control group on the Rey Auditory Verbal Learning Test 3; (F(2,53) =3.500, p=0.038) and 7 (F(2,53) =5.068, p=0.010). The clinical groups had elevated levels of depression on the Beck Depression Inventory (BDI); (p=0.003). The analysis of the data from the Trail Making Test B-A revealed a significant difference between the clinical and control groups (p=0.023). The analysis of covariance with BDI score as a covariate, did not change the outcome.

CONCLUSION:

Our study revealed cognitive deficits in patients with PSS detectable by a short neuropsychological battery.

PMID:
24637981
DOI:
10.1590/0004-282X20130195
[Indexed for MEDLINE]
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