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Methods. 2014 Jun 15;68(1):38-47. doi: 10.1016/j.ymeth.2014.03.007. Epub 2014 Mar 15.

Navigating and mining modENCODE data.

Author information

1
Department of Biostatistics, University of California Berkeley, Berkeley, CA, United States.
2
Department of Genome Dynamics, Lawrence Berkeley National Laboratory, Berkeley, CA, United States.
3
Department of Statistics, University of California Berkeley, Berkeley, CA, United States.
4
Department of Genome Dynamics, Lawrence Berkeley National Laboratory, Berkeley, CA, United States. Electronic address: celniker@fruitfly.org.

Abstract

modENCODE was a 5year NHGRI funded project (2007-2012) to map the function of every base in the genomes of worms and flies characterizing positions of modified histones and other chromatin marks, origins of DNA replication, RNA transcripts and the transcription factor binding sites that control gene expression. Here we describe the Drosophila modENCODE datasets and how best to access and use them for genome wide and individual gene studies.

KEYWORDS:

Chromatin; Drosophila; Mining; Transcription; modENCODE

PMID:
24636835
PMCID:
PMC4857704
DOI:
10.1016/j.ymeth.2014.03.007
[Indexed for MEDLINE]
Free PMC Article

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