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Australas J Dermatol. 2014 Aug;55(3):169-75. doi: 10.1111/ajd.12163. Epub 2014 Mar 17.

Nicotinamide and the skin.

Author information

1
Discipline of Dermatology, Bosch Institute, Central Clinical School, University of Sydney, Sydney, New South Wales, Australia; Department of Dermatology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

Abstract

Nicotinamide, an amide form of vitamin B3, boosts cellular energy and regulates poly-ADP-ribose-polymerase 1, an enzyme with important roles in DNA repair and the expression of inflammatory cytokines. Nicotinamide shows promise for the treatment of a wide range of dermatological conditions, including autoimmune blistering disorders, acne, rosacea, ageing skin and atopic dermatitis. In particular, recent studies have also shown it to be a potential agent for reducing actinic keratoses and preventing skin cancers.

KEYWORDS:

nicotinamide; skin cancer; skin disease

PMID:
24635573
DOI:
10.1111/ajd.12163
[Indexed for MEDLINE]

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