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Neurology. 2014 Apr 15;82(15):1380-1. doi: 10.1212/WNL.0000000000000324. Epub 2014 Mar 14.

Damping of monocular pendular nystagmus with vibration in a patient with multiple sclerosis.

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1
From The Johns Hopkins Hospital, Baltimore, MD.

Abstract

Acquired pendular nystagmus (PN) occurs commonly in multiple sclerosis (MS) and results in a highly disabling oscillopsia that impairs vision. It usually consists of pseudo-sinusoidal oscillations at a single frequency (3-5 Hz) that often briefly stop for a few hundred milliseconds after saccades and blinks. The oscillations are thought to arise from instability in the gaze-holding networks ("neural integrator") in the brainstem and cerebellum.(1,2) Here we describe a patient with monocular PN in whom vibration on the skull from a handheld muscle massager strikingly diminished or stopped her nystagmus.

PMID:
24634455
PMCID:
PMC4001187
DOI:
10.1212/WNL.0000000000000324
[Indexed for MEDLINE]
Free PMC Article
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