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Magn Reson Imaging. 2014 Jun;32(5):594-7. doi: 10.1016/j.mri.2014.01.019. Epub 2014 Jan 31.

3D high-resolution contrast enhanced MRI of carotid atheroma--a technical update.

Author information

1
University Department of Radiology, University of Cambridge, Cambridge, CB2 0QQ, UK. Electronic address: cz254@cam.ac.uk.
2
Vascular Surgery Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK.
3
University Department of Radiology, University of Cambridge, Cambridge, CB2 0QQ, UK.

Abstract

OBJECTIVE:

Development of a fast 3D high-resolution magnetic resonance imaging (MRI) protocol for improved carotid artery plaque imaging.

METHODS:

Two patients with carotid atherosclerosis disease underwent 3D high-resolution MRI which included time-of-flight and T1-weighted variable flip angle, fast-spin-echo (FSE) imaging, pre- and post-intravenous gadolinium-based contrast agent administration.

RESULTS:

Good quality images with intrinsic blood suppression were obtained pre- and post-contrast administration using a 3D FSE sequence. The plaque burden, lipid core volume, hemorrhage volume and fibrous cap thickness were well determined.

CONCLUSIONS:

3D high-resolution MR imaging of carotid plaque using TOF and 3D FSE can achieve high isotropic resolution, large coverage, and excellent image quality within a short acquisition time.

KEYWORDS:

3D Fast Spin Echo; Carotid atheroma; Fibrous cap; Hemorrhage; Lipid core

PMID:
24630443
DOI:
10.1016/j.mri.2014.01.019
[Indexed for MEDLINE]

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