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An Bras Dermatol. 2014 Jan-Feb;89(1):173-4. doi: 10.1590/abd1806-4841.20142431.

Case for diagnosis. Cutaneous involvement associated to multiple myeloma.

Author information

1
Centro Hospital de Lisboa Central, Santo António dos Capuchos Hospital, Lisbon, Portugal, Dermatology and Venereology Resident at the Santo António dos Capuchos Hospital - Centro Hospital de Lisboa Central (CHLC) - Lisbon, Portugal.
2
São Bernardo Hospital, Setúbal, Portugal, Dermatology and Venereology Consultant at the São Bernardo Hospital, Setúbal, Portugal.
3
Centro Hospital de Lisboa Central, Santo António dos Capuchos Hospital, Lisbon, Portugal, Consultant of Hematology of the Santo António dos Capuchos Hospital - Centro Hospital de Lisboa Central (CHLC) - Lisbon, Portugal.
4
Centro Hospital de Lisboa Central, Santo António dos Capuchos Hospital, Lisbon, Portugal, Dermatology and Venereology Consultant at the Santo António dos Capuchos Hospital - Centro Hospital de Lisboa Central (CHLC) - Lisbon, Portugal.

Abstract

Cutaneous involvement associated to multiple myeloma varies from 5 to 10% of cases and is infrequently recognized. Cutaneous metastatic plasmacitomas are rare. We present the case of a 72-year-old man with multiple myeloma in complete remission since 2 years ago with cutaneous tumors on the trunk and face. A cutaneous biopsy was consistent with plasmacytoma. The patient was treated with melphalan, prednisolone and radiotherapy. Despite optimal therapeutic response of the lesions, the disease progressed, with the appearance of new extra-cutaneous plasmocytomas. The cutaneous metastatic plasmocytomas were the first sign of progression of the disease.

PMID:
24626671
PMCID:
PMC3938377
DOI:
10.1590/abd1806-4841.20142431
[Indexed for MEDLINE]
Free PMC Article

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