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Expert Rev Pharmacoecon Outcomes Res. 2014 Apr;14(2):195-202. doi: 10.1586/14737167.2014.898565.

Vaccination planning and vaccine prices in a decentralizing country - Italy.

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IRCCS Institute for Pharmacological Research 'Mario Negri', Ranica, Italy.


This paper gives an overview, in the era of regionalization, of vaccination planning and vaccine price management in the Italian National Health Service. In particular, we analyse the current National Vaccination Plan (NVP) and end with two "case studies" of the latest entries in the Italian vaccination calendar, comparing HPV and PCV vaccines, the most expensive ones in Italy at present. The present NVP put an end to the long period without official documents for vaccination planning, mainly reflecting the controversial relationships between the national and regional tiers. However, this document is not really useful for planning from the health professionals' point of view, lacking epidemiological information. Thorough systematic assessment of the new, expensive vaccines is becoming a real priority in the light of current financial difficulties. In this perspective, the two examples discussed have given different results so far, starting from a heterogeneous situation of potential market competition.

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