Format

Send to

Choose Destination
See comment in PubMed Commons below
J Org Chem. 2014 Apr 4;79(7):3052-9. doi: 10.1021/jo5001719. Epub 2014 Mar 19.

From propargylamides to oxazole derivatives: NIS-mediated cyclization and further oxidation by dioxygen.

Author information

1
Dalian Institute of Chemical Physics, Chinese Academy of Sciences , 457 Zhongshan Road, Dalian 116023, People's Republic of China.

Abstract

NIS-mediated iodocyclization of N-sulfonyl propargylamides for the synthesis of various oxazolidines and iodoalkylidenedihydrooxazoles via a 5-exo-dig process is developed. The resulting iodoalkylidenedihydrooxazoles can be further transformed into the corresponding oxazoles in the presence of dioxygen.

PMID:
24620818
DOI:
10.1021/jo5001719
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Support Center