Format

Send to

Choose Destination
See comment in PubMed Commons below
J Am Coll Cardiol. 2014 May 13;63(18):1815-22. doi: 10.1016/j.jacc.2014.02.529. Epub 2014 Mar 5.

Pre-eclampsia and future cardiovascular risk among women: a review.

Author information

1
Faculty of Medical Sciences, Newcastle University Medical School, Newcastle upon Tyne, United Kingdom.
2
Mount Sinai School of Medicine, New York, New York.
3
Uterine Cell Signaling Group, Newcastle University, Newcastle upon Tyne, United Kingdom; Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
4
Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom; Cardiothoracic Centre, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom. Electronic address: vijay.kunadian@newcastle.ac.uk.

Abstract

Cardiovascular disease continues to be the leading cause of death in the western world. Due to advancements in diagnosis, prevention, and treatment, cardiovascular mortality has fallen in recent years. Previous studies have evaluated the impact of traditional risk factors such as hypercholesterolemia and smoking. However, limited studies have been conducted to evaluate sex discrepancies among patients with cardiovascular disease. Pre-eclampsia is a multisystem placentally mediated disease, which usually arises after 32 weeks of gestation and classically presents with hypertension and proteinuria. Pre-eclampsia affects 2% to 8% of all pregnancies worldwide and is often complicated by fetal growth restriction. Women with a history of pre-eclampsia are at increased risk of future cardiovascular complications. Therefore, this topic is of significance to the cardiovascular health of over 300 million women worldwide. The goal of this review is to determine the association of pre-eclampsia and future cardiovascular risk and to explore the potential management options for these high-risk women.

KEYWORDS:

acute coronary syndrome; angina; coronary artery disease; endothelium; hypertension; myocardial infarction; pre-eclampsia; vascular function

PMID:
24613324
DOI:
10.1016/j.jacc.2014.02.529
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center