Format

Send to

Choose Destination
See comment in PubMed Commons below
Mod Rheumatol. 2014 Nov;24(6):966-73. doi: 10.3109/14397595.2014.883055. Epub 2014 Mar 4.

Association of knee osteoarthritis with onset and resolution of pain and physical functional disability: the ROAD study.

Author information

1
Department of Clinical Motor System Medicine, 22nd Century Medical & Research Center, Faculty of Medicine, the University of Tokyo , Tokyo , Japan.

Abstract

OBJECTIVES:

To examine the onset and resolution of pain and physical functional disability using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and their association with knee osteoarthritis (OA) in the longitudinal large-scale population of the nationwide cohort study, Research on Osteoarthritis/osteoporosis Against Disability (ROAD).

METHODS:

Subjects from the ROAD study who had been recruited during 2005-2007 were followed up 3 years later. A total of 1,578 subjects completed the WOMAC questionnaire at baseline and follow up, and the onset and resolution rate of pain and physical functional disability were examined. We also examined the association of onset of pain and physical functional disability and their resolution with severity of knee OA as well as age, body-mass index and grip strength.

RESULTS:

After a 3.3-year follow-up, the onset rate of pain was 35.0% and 35.3% in men and women, respectively, and the onset rate of physical functional disability was 38% and 40%, respectively. Resolution rate of pain was 20.3% and 26.2% in men and women, respectively, and resolution rate of physical functional disability was 16% and 14% in men and women, respectively. Knee OA was significantly associated with onset and resolution of pain and physical functional disability in women, but there was no significant association of knee OA with onset of pain and resolution of physical functional disability in men.

CONCLUSIONS:

The present longitudinal study revealed the onset rate of pain and physical functional disability as well as their resolution, and their association with knee OA.

KEYWORDS:

Epidemiology; Knee joint; Longitudinal studies; Osteoarthritis

PMID:
24593166
DOI:
10.3109/14397595.2014.883055
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments

    Supplemental Content

    Full text links

    Icon for Taylor & Francis
    Loading ...
    Support Center