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Nepal Med Coll J. 2013 Mar;15(1):62-4.

Effect of continuous light on spermatogenesis and testicular steroidogenesis in rats: possible involvement of alpha 2u-globulin.

Author information

1
Department of Physiology, College of Medical Sciences, Bharatpur, Chitwan, Nepal. drnmbiswas@gmail.com
2
Department of Physiology, College of Medical Sciences, Bharatpur, Chitwan, Nepal.
3
Departmental of Medicine, NRS Medical College, Kolkata-14, India.

Abstract

Male rats exposed to continous light for 70 days showed an increased weights of testis, accessory sex organs, serum levels of FSH, LH, testosterone, testicular 17beta-hydroxysteroid dehydrogenase (1beta-HSD) activity and alpha 2u-globulin, while 3beta-hydroxysteroid dehydrogenase activity showed no significant changes. Prolonged light exposure also stimulated sepermatogenesis in rats. These results suggest that alpha 2u-globulin possibly stimutates the male gonad by inducing pituitary gonadotropins in continuous light-exposed rats.

PMID:
24592797
[Indexed for MEDLINE]

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