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Methods Mol Biol. 2014;1140:53-9. doi: 10.1007/978-1-4939-0354-2_4.

Selecting targets from eukaryotic parasites for structural genomics and drug discovery.

Author information

1
Seattle Structural Genomics Center for Infectious Disease, Seattle, WA, USA.

Abstract

The selection of targets is the first step for any structural genomics project. The application of structural genomics approaches to drug discovery also starts with the selection of targets. Here, three protocols are described that were developed to select targets from eukaryotic pathogens. These protocols could also be applied to other drug discovery projects.

PMID:
24590708
PMCID:
PMC4601580
DOI:
10.1007/978-1-4939-0354-2_4
[Indexed for MEDLINE]
Free PMC Article

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