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PLoS One. 2014 Feb 19;9(2):e89120. doi: 10.1371/journal.pone.0089120. eCollection 2014.

Population structure of Staphylococcus aureus from Trinidad & Tobago.

Author information

1
Institute for Medical Microbiology and Hygiene, Technical University of Dresden, Dresden, Germany ; Alere Technologies GmbH, Jena, Germany.
2
Department of Para-Clinical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
3
Alere Technologies GmbH, Jena, Germany.

Abstract

It has been shown previously that high rates of methicillin- and mupirocin-resistant Staphylococcus aureus exist in the Caribbean islands of Trinidad and Tobago, as well as a high prevalence of Panton-Valentine leukocidin-positive S. aureus. Beyond these studies, limited typing data have been published. In order to obtain insight into the population structure not only of MRSA but also of methicillin-susceptible S. aureus, 294 clinical isolates collected in 2012/2013 were typed by microarray hybridisation. A total of 15.31% of the tested isolates were MRSA and 50.00% were PVL-positive. The most common MSSA strains were PVL-positive CC8-MSSA (20.41% of all isolates tested), PVL-positive CC152-MSSA (9.52%) and PVL-positive CC30-MSSA (8.84%) while the most common MRSA were ST239-MRSA-III&SCCmer (9.18%) and ST8-MRSA-IV, "USA300" (5.78%). 2.38% of characterised isolates belonged to distinct strains likely to be related to "Staphylococcus argenteus" lineages. The population structure of S. aureus isolates suggests an importation of strains from Africa, endemicity of PVL-positive MSSA (mainly CC8) and of ST239-MRSA-III, and a recent emergence of the PVL-positive CC8-MRSA-IV strain "USA300".

PMID:
24586536
PMCID:
PMC3929661
DOI:
10.1371/journal.pone.0089120
[Indexed for MEDLINE]
Free PMC Article

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