Format

Send to

Choose Destination
Mymensingh Med J. 2014 Jan;23(1):181-5.

Acne vulgaris related to androgens - a review.

Author information

1
Dr Lubna Khondker, Assistant Professor, Department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka, Bangladesh.

Abstract

Sebum production is stimulated by androgens and is the key in the development of acne vulgaris. Several investigators have looked for direct relationships between serum androgen levels, sebum secretion rate and the presence of acne. The presence of acne in prepubertal girls and sebum production in both sexes correlate with serum dehydroepiandrosterone sulfate (DHEAS) levels. Although increased serum androgen levels correlate with the presence of severe nodular acne in men and women, these levels are often within the normal range in mild to moderate acne. This raises the question of whether there is an increased local production of androgens within the sebaceous gland of patients with acne vulgaris that leads to increased sebum secretion.

PMID:
24584396
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center