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Phytochemistry. 2014 May;101:91-100. doi: 10.1016/j.phytochem.2014.02.007. Epub 2014 Feb 28.

Monoterpene glycosides, phenylpropanoids, and acacetin glycosides from Dracocephalum foetidum.

Author information

1
Department of Pharmacognosy, Tohoku Pharmaceutical University, 4-1 Komatsushima 4-chome Aoba-ku, Sendai 981-8558, Japan.
2
Department of Pharmacognosy, Tohoku Pharmaceutical University, 4-1 Komatsushima 4-chome Aoba-ku, Sendai 981-8558, Japan. Electronic address: murata-t@tohoku-pharm.ac.jp.
3
School of Biology and Biotechnology, National University of Mongolia, PO Box 617, Ulaanbaatar 46A, Mongolia.

Abstract

Chemical investigation of the acetone extract from the aerial parts of the Mongolian medicinal plant Dracocephalum foetidum resulted in the isolation of three limonene glycosides, a caffeic acid trimer, four rosmarinic acid glucosides, and five acacetin acyl glycosides, together with 13 known natural products. The chemical structures of all of the compounds were determined by spectroscopic analyses. Among these compounds three showed hyaluronidase inhibitory activity. In addition, one other compound showed stronger 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity than the positive control Trolox, whereas three other compounds demonstrated a similar activity to that of Trolox.

KEYWORDS:

DPPH radical scavenging activity; Dracocephalum foetidum; Hyaluronidase inhibitory activity; Lamiaceae; Limonene glycoside; Phenylpropanoid

PMID:
24582463
DOI:
10.1016/j.phytochem.2014.02.007
[Indexed for MEDLINE]
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