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J Arthroplasty. 2014 Jul;29(7):1398-411. doi: 10.1016/j.arth.2014.01.012. Epub 2014 Jan 21.

A systematic review of clinical outcomes and survivorship after total knee arthroplasty with a contemporary modular knee system.

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DePuy International Ltd., Leeds, United Kingdom.
St. Joseph Medical Center, Baltimore, Maryland.


A systematic review appraising the clinical performance and safety of the primary SIGMA modular knee system (DePuy-Synthes, Warsaw, Ind.) found 5 registry reports and 53 journal publications reporting survivorship or postoperative increase in Knee Society scores on 241632 primary SIGMA knee arthroplasties. Pooled data from national joint registries and clinical studies on primary SIGMA knee survivorship were comparable. Both were higher than for all other knees in 5 national joint registries up to 5 years. Compared with pooled data from 2 independent systematic reviews of primary non-SIGMA knees, the SIGMA system provided comparable postoperative changes in Knee Society knee score and a nonsignificant trend of higher postoperative changes in Knee Society function score. This finding suggests that this knee system provides excellent durable results.


SIGMA knee; modular knee system; survivorship; systematic review; total knee arthroplasty

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