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Neuroradiol J. 2014 Feb;27(1):85-90. Epub 2014 Feb 24.

Acute ischemic stroke secondary to glioblastoma. A case report.

Author information

1
Serviço de Neurorradiologia, Hospital de Santo António - CHP; Porto, Portugal - sofiapina@mail.com.
2
Serviço de Neurorradiologia, Hospital de Santo António - CHP; Porto, Portugal.

Abstract

Glioblastoma is a malignant infiltrative glial tumor occurring most often over 50 years of age, with diverse clinical presentations. We describe a case of temporal lobe glioblastoma with a rare presentation as an acute ischemic stroke, discussing the imaging and histopathological findings, and reviewing the literature. A 77-year-old woman had sudden onset of left hemiparesis and hemihypoesthesia. The neuroradiological studies revealed an acute ischemic lesion in the right lenticulostriate arteries territory and a right anterior temporal lobe tumor, enhancing heterogeneously after contrast with enhancement of the right middle cerebral artery wall. Histopathological analysis of the resected temporal lesion revealed a glioblastoma multiforme with tumoral infiltration of the vascular wall. Glioblastoma should be considered in the etiology of acute ischemic stroke, where neuroimaging plays an important diagnostic role, enabling a more immediate therapeutic approach, with a consequent impact on survival.

KEYWORDS:

computed tomography; glioblastoma; magnetic resonance imaging; stroke; vasculopathy

PMID:
24571837
PMCID:
PMC4202841
DOI:
10.15274/NRJ-2014-10009
[Indexed for MEDLINE]
Free PMC Article
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