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Nat Genet. 2014 Mar;46(3):215-7. doi: 10.1038/ng.2903.

The epigenetic sole of sex and dosage compensation.

Author information

1
La Trobe Institute of Molecular Science, Melbourne, Victoria, Australia.

Abstract

Sex chromosomes in mammals, birds, reptiles and fish represent many independent evolutionary events, but there is spectacular convergence and stunning parallels. A new study details the early stages of ZW differentiation and sex determination in a flatfish and the establishment of dosage compensation and sex reversal by epigenetic mechanisms including DNA methylation.

PMID:
24569234
DOI:
10.1038/ng.2903
[Indexed for MEDLINE]

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