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J AAPOS. 2014 Feb;18(1):26-30. doi: 10.1016/j.jaapos.2013.10.016.

Office probing for treatment of nasolacrimal duct obstruction in infants.

Collaborators (242)

Sala NA, Donahue S, Morrison DG, Hoover DL, Lee KA, Crouch ER Jr, Crouch ER 3rd, Klimek DL, Weakley DR Jr, Itani KM, Schloff S, Hickson AM, Bremer DL, Bean CM, Golden RP, McGregor ML, Rogers GL, Tien DR, Arnold RW, Goldblum TA, Ticho BH, Khammar AJ, Fishman DR, Verderber LC, Silbert DI, Blackburn DD, Hosey TJ, Singman EL, Lee DH, Caltrider ND, Atkinson S, Paysse EA, Coats DK, Edmond JC, Steinkuller PG, Yen KG, Levada AJ, Silbert JE, Astle WF, Ashenhurst ME, Ells AL, Hill VE, Kherani F, Romanchuk KG, Suh DW, Stager DR Sr, Stager DR Jr, Bacal DA, Forbes BJ, Katowitz JA, Quinn GE, Trigler L, Siatkowski R, Ruben JB, Cruz OA, Davitt BV, Roberts JT, Summers C, Bothun ED, Christiansen SP, Gearinger MD, Collins ML, Perla BD, Lambert SR, Hutchinson AK, Levin EM, Del Monte MA, Eibschitz-Tsimhoni M, Braverman RS, Curtis TH, Drack AV, Bartiss MJ, Wheeler DT, Ng JD, Stout AU, Repka MX, Eibschitz-Tsimhoni M, Levin EM, Droste PJ, Peters RJ, Bradfield YS, France TD, Holmes JM, Mohney BG, Glaser SR, Jensen AA, Donahue JP, Sala NA, Hodde RM, Zeto VL, Lee KA, Schweinler BR, Plum LW, Petersen DB, McMurtrey J, Tien DR, Yoon-Huang GH, McGuinness MB, De La Rosa JM, Bailey CM, Marinaro JA, Ticho BH, Khammar AJ, Clausius DA, Coletta JB, Imler BC, Bremer DL, Cassady CM, Golden RP, McGregor ML, Rogers DL, Rogers GL, Fellows RR, McMillin MC, Rinehart TM, Wagner AJ, Brendez JA, Cox RE, Weakley DR Jr, Dias CL, Zhang XW, Crouch ER, Crouch ER, Ventura GG, Morrison DG, Fraine LA, Biernacki RJ, Franklin CC, Haskins KJ, Hoover DL, Huston PA, Lambert SR, Hutchinson AK, Lenhart PD, Shainberg MJ, Robb RA, Couser NL, Morse CL, Fang CC, Christian ML, Karlsson VX, Traboulsi E, Rychwalski PJ, Crowe SW, Silbert DI, Singman EL, Matta NS, Leckemby GL, Pavlica MR, Summers C, Bothun ED, De Becker I, Holleschau AM, de Melo AI, Hogue KM, Merrill KS, Miller AM, Jackson JL, LaRiviere SS, Goldblum TA, Alfaro A, Atkinson S, Trythall CL, Hendrickson AB, Avallone JM, Bryant CR, Peyton WE, Orge FH, Schoeck SE, Colon BJ, Mar NX, Vaswani RS, Weisberg OL, Giansanti SM, Kaddy JM, Kraker RT, Beck RW, Cagnina-Morales CM, Chandler DL, Clark LE, Costa C, Diamond ER, Donahue Q, Fimbel BP, Foster NC, Lazar EL, Lee SV, Lester LA, Melia B, Moke PS, Rojas DE, Everett DF, Repka MX, Lee KA, Holmes JM, Chandler DL, Frick K, Silbert DI, Sala NA, Hoover DL, Beck RW, Lee KA, Repka MX, Holmes JM, Chandler DL, Everett DF, Zeto VL, Fellows RR, Holmes JM, Beck RW, Birch EE, Everett DF, Kraker RT, Repka MX, Cotter SA, Wallace DK, Petersen DB, Enyedi L, Hoover DL, Rogers DL, Miller AM, Jackson JL, Kulp MT, Ticho BH, Crouch ER 3rd, Bacal D, Rutstein R, Christiansen S, Huston P, Lee KA, Matta NS, Morrison D, Scheiman M, Diener-West M, Baker JD, Davis B, Dobson V, Everett DF, Phelps DL, Poff S, Saunders RA, Tychsen L.

Author information

1
Houston Eye Associates, The Woodlands, Texas. Electronic address: pedignld3prob@jaeb.org.
2
Jaeb Center for Health Research, Tampa, Florida.
3
Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland.
4
Everett and Hurite Ophthalmic Association, Cranberry TWP, Pennsylvania.
5
St. Luke`s Children's Ophthalmology, Boise, Idaho.
6
Cole Eye Institute, Cleveland, Ohio.
7
Family Eye Group, Lancaster, Pennsylvania.

Abstract

PURPOSE:

To determine whether demographic or clinical factors are associated with the outcome of office-based nasolacrimal duct probing for the treatment of congenital nasolacrimal duct obstruction (NLDO).

METHODS:

In two multicenter prospective studies, 384 eyes of 304 children aged 6 to <15 months with NLDO underwent a nasolacrimal duct probing performed in the office using topical anesthesia. Treatment success, defined as no clinical signs of NLDO (epiphora, increased tear lake, or mucous discharge) and no reoperation, was assessed 1 month after probing in one study and 6 months after probing in the other study. Data from both studies were pooled to evaluate associations between baseline characteristics and treatment success.

RESULTS:

Office probing was successful in 75% of eyes overall (95% CI, 70%-80%). The procedure was less successful in eyes of children with bilateral NLDO compared with unilateral NLDO (63% vs 80%; relative risk = 0.78 [95% CI, 0.66-0.92]) and in eyes that had 2 or 3 clinical signs of NLDO compared with one (71% vs 83%; relative risk = 0.88 [95% CI, 0.81-0.96]). Treatment success did not appear to be related to age, specific clinical signs of NLDO, prior treatment, or research study.

CONCLUSIONS:

Performing nasolacrimal duct probing in the office successfully treats NLDO in the majority of cases in children aged 6 to <15 months. The success rate is lower with bilateral disease or when more than one clinical sign of NLDO is present.

TRIAL REGISTRATION:

ClinicalTrials.gov NCT00315289 NCT00780741.

PMID:
24568978
PMCID:
PMC3936253
DOI:
10.1016/j.jaapos.2013.10.016
[Indexed for MEDLINE]
Free PMC Article

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