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Chem Commun (Camb). 2014 Apr 7;50(27):3560-3. doi: 10.1039/c3cc49036j.

Spatially marking and quantitatively counting membrane immunoglobulin M in live cells via Ag cluster-aptamer probes.

Author information

1
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, P. R. China. gaoxy@ihep.ac.cn.

Abstract

A probe composed of an aptamer and a silver cluster, where the aptamer targets mIgM of live cells and the silver cluster provides fluorescent imaging and mass quantification of mIgM of live cells, is presented. This new probe simultaneously provides accurate spatial and mass information of mIgM in live cells.

PMID:
24563906
DOI:
10.1039/c3cc49036j
[Indexed for MEDLINE]
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