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EMBO J. 2014 Mar 18;33(6):534-5. doi: 10.1002/embj.201487976. Epub 2014 Feb 20.

Sex hormone drives blood stem cell reproduction.

Author information

1
Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.

Abstract

Stem cells ensure the maintenance of tissue homeostasis throughout life by tightly regulating their self-renewal and differentiation. In a recent study published in Nature, Nakada et al, 2014 unveil an unexpected endocrine mechanism that regulates hematopoietic stem cell (HSC) self-renewal.

PMID:
24562387
PMCID:
PMC3989647
DOI:
10.1002/embj.201487976
[Indexed for MEDLINE]
Free PMC Article

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