[The role of kidney transplantation in reducing mortality in a chronic dialysis program]

Medicina (B Aires). 2014;74(1):1-8.
[Article in Spanish]

Abstract

For patients with chronic renal failure (CRF), kidney transplant (KT) is a better alternative to dialysis in terms of survival, life quality and costs. We studied the general characteristics, causes and survival rate of the dialysis population in 2010. We evaluated broader criteria for acceptance of transplants has affected the results of the procedure in that period. A total of 118 dialysis patients were included; mean age 56.9 ± 18.4 years, dialysis duration 45.5 ± 59.6 months, main cause of CRF was diabetes in 35 (30%), and 58 (49%) were included in waiting list for KT. Of the 34 patients who finished dialysis in 2010, 18 (53%) were KT, while 12 (35%) died (cardiovascular 50%, infectious 17%). Survival at 12 months was 85% for the total group, 98% on waiting list and 72% those who were not enrolled. During 2010 there were 88 KT, 62 with cadaveric donors (CD), 18 with living donors and 8 with double pancreas-kidney transplants. Recipients of CD were 50.7 years old, with 67 months on dialysis, 8 (13%) diabetics, and 12 (20%) with previous KT. Donors had a mean age of 45 years, 28 (45%) expanded criteria, and 27.7 hours of cold ischemia time. During an approximate follow-up of 11.4 months, 13 (21%) suffered acute graft rejection, survival was 88% for graft and 93% for patients. We emphasize KT as the main cause of success as regards dialysis. No differences in risk factors were found to significantly affect graft or patient survival.

Keywords: chronic kidney disease; dialysis; kidney transplant.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Argentina / epidemiology
  • Cadaver
  • Chronic Disease
  • Female
  • Follow-Up Studies
  • Graft Rejection
  • Hemodialysis Units, Hospital / statistics & numerical data
  • Humans
  • Incidence
  • Kidney Transplantation / mortality*
  • Kidney Transplantation / statistics & numerical data
  • Male
  • Middle Aged
  • Peritoneal Dialysis / mortality
  • Prevalence
  • Renal Dialysis / mortality*
  • Renal Dialysis / statistics & numerical data
  • Survival Rate*
  • Tissue Donors
  • Waiting Lists