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Diagn Microbiol Infect Dis. 2014 May;79(1):70-2. doi: 10.1016/j.diagmicrobio.2014.01.007. Epub 2014 Jan 24.

First report of plasmid-mediated fluoroquinolone efflux pump QepA in Escherichia coli clinical isolate ST68, in South America.

Author information

1
Dpto. de Microbiología, CABA, Universidad de Buenos Aires, Buenos Aires, Argentina; Universidad Industrial de Santander, Santander, Colombia.
2
Dpto. de Microbiología, CABA, Universidad de Buenos Aires, Buenos Aires, Argentina.
3
Hospital Británico, Buenos Aires, Argentina.
4
Dpto. de Microbiología, CABA, Universidad de Buenos Aires, Buenos Aires, Argentina; Cátedra de Microbiología General, Universidad Nacional del Litoral, Santa Fe, Argentina. Electronic address: jdiconza@gmail.com.

Abstract

This is the first report of the presence of qepA1 efflux pump gene in Escherichia coli clinical isolate from Argentina, which was associated to other plasmid-mediated quinolone resistance determinants, such as aac(6')-Ib-cr and qnrB10 and also quinolone resistance determining regions mutations.

KEYWORDS:

Fluoroquinolone resistance; PMQR; QRDR; qepA

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