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J Clin Exp Dent. 2012 Feb 1;4(1):e40-2. doi: 10.4317/jced.50691. eCollection 2012 Feb.

Utility of Periodontal exploration in patients with Fibromyalgia.

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Departamento de periodontología, Facultad de Odontología, Universidad de Sevilla, Spain.
Centro Andaluz de Biología del Desarrollo (CABD), Universidad Pablo de Olavide-CSIC and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), ISCIII, Sevilla, Spain.
Director del Master de Periodoncia e Implantología, Facultad de Odontología, Universidad de Sevilla, Spain.



[corrected] Fibromyalgia (FM) is a chronic pain syndrome with unknown etiology, which affects predominantly women. Mitochondrial alteration could have a role in the pathophysilogical mechanisms of inflammatory conditions as FM and periodontitis. The aim of the present study was assay the relationship between both diseases and mitochondrial dysfunction.


We study the presence of periodontitis in twelve patients diagnosed of FM and mitochondrial dysfunction described. The diagnosis of FM was established according to ACR criteria and clinical symptoms were evaluated using the Fibromyalgia Impact Questionnaire (FIQ) and Beck Depression Inventory (BDI).


Only one patients of twelve included and agreed to participate in the study were diagnosed with periodontitis.


Pending studies with larger numbers of patients, we can conclude that mitochondrial dysfunction in FM is a itself event not related with periodontitis. Periodontitis could be considered a exclusion criterion in all studies about mitochondrial dysfunction in patients. Key words:Peridontitis, fibromyalgia, mitocondrial dysfunction, oxidative stress.

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