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G3 (Bethesda). 2014 Apr 16;4(4):761-7. doi: 10.1534/g3.113.010140.

Saccharomyces cerevisiae essential genes with an Opi- phenotype.

Author information

1
Department of Microbiology, and Molecular Cellular Biology Graduate Program, University of Massachusetts, Amherst, Massachusetts 01003.

Abstract

The overproduction and secretion of inositol (i.e., Opi(-)) phenotype is associated with defects in regulation of phospholipid biosynthesis in yeast. Here we report a screen of the essential yeast gene set using a conditional-expression library. This screen identified novel functions previously unknown to affect phospholipid synthesis.

KEYWORDS:

inositol; phospholipid synthesis; regulation; transcription; yeast

PMID:
24558266
PMCID:
PMC4059245
DOI:
10.1534/g3.113.010140
[Indexed for MEDLINE]
Free PMC Article

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