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Angiology. 2014 Oct;65(9):844-8. doi: 10.1177/0003319714522106. Epub 2014 Feb 19.

Association of glomerular filtration rate with slow coronary flow in patients with normal to mildly impaired renal function.

Author information

1
Department of Cardiology, Muğla Sitki Kocman University School of Medicine, Mugla, Turkey fatih._akin@hotmail.com.
2
Department of Cardiology, Mehmet Akif Ersoy Chest and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.
3
Department of Cardiology, Bağcilar Education and Research Hospital, Istanbul, Turkey.
4
Department of Cardiology, Muğla Sitki Kocman University School of Medicine, Mugla, Turkey.
5
Department of Cardiology, Muğla Yucelen Hospital, Mugla, Turkey.

Abstract

We evaluated the association between estimated glomerular filtration rate (eGFR) and slow coronary flow (SCF) in patients with normal to mildly impaired renal function; 211 patients with angiographically proven SCF and 219 controls were studied. Patients were categorized based on the angiographic findings as with or without SCF. We used the Modification of Diet in Renal Disease equation to calculate eGFR. The frequency of mildly decreased eGFR, serum uric acid levels, and eGFR was higher in the SCF group. Patients with mildly impaired renal function had higher thrombolysis in myocardial infarction frame counts in 3 major coronary arteries. In logistic regression analysis, uric acid (odds ratio [OR] = 1.323, 95% confidence interval [CI] = 1.109-1.572, P = .002) and eGFR (OR = 0.972, 95% CI = 0.957-0.987, P < .001) were independent correlates of SCF. In conclusion, eGFR was significantly correlated with SCF in patients with normal to mildly impaired renal function.

KEYWORDS:

glomerular filtration rate; renal function; slow coronary flow; uric acid

PMID:
24554428
DOI:
10.1177/0003319714522106
[Indexed for MEDLINE]
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