Format

Send to

Choose Destination
Behav Genet. 2014 Mar;44(2):91-6. doi: 10.1007/s10519-014-9644-z. Epub 2014 Feb 20.

Common genetic variants explain the majority of the correlation between height and intelligence: the generation Scotland study.

Author information

1
Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK, riccardo.marioni@ed.ac.uk.

Abstract

Greater height and higher intelligence test scores are predictors of better health outcomes. Here, we used molecular (single-nucleotide polymorphism) data to estimate the genetic correlation between height and general intelligence (g) in 6,815 unrelated subjects (median age 57, IQR 49-63) from the Generation Scotland: Scottish Family Health Study cohort. The phenotypic correlation between height and g was 0.16 (SE 0.01). The genetic correlation between height and g was 0.28 (SE 0.09) with a bivariate heritability estimate of 0.71. Understanding the molecular basis of the correlation between height and intelligence may help explain any shared role in determining health outcomes. This study identified a modest genetic correlation between height and intelligence with the majority of the phenotypic correlation being explained by shared genetic influences.

PMID:
24554214
PMCID:
PMC3938855
DOI:
10.1007/s10519-014-9644-z
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Springer Icon for PubMed Central
Loading ...
Support Center