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Adv Mater. 2014 May 21;26(19):3124-30. doi: 10.1002/adma.201305506. Epub 2014 Feb 18.

3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs.

Author information

1
School of Engineering and Applied Sciences, Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA, 02138, USA.

Abstract

A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new -avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches.

KEYWORDS:

3D printing; biomaterials; bioprinting; tissue engineering; vasculature

PMID:
24550124
DOI:
10.1002/adma.201305506
[Indexed for MEDLINE]

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