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Brain Res. 1988 Apr 26;447(1):164-8.

Colocalization of substance P and gamma-aminobutyric acid in amacrine cells of the cat retina.

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  • 1Department of Anatomy and Cell Biology, Wayne State University, Detroit, MI 48201.


Substance P and gamma-aminobutyric acid (GABA) were colocalized by immunocytochemistry in two subpopulations of amacrine cells in the cat retina. All of the cells which stained for substance P also showed GABA reactivity. However, there were many GABA-immunoreactive cells which did not stain for substance P. The presence of neuropeptides provides a basis for additional neurochemical characterization of the multiple populations of GABA immunoreactive cells.

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