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FEBS Lett. 1988 May 23;232(2):323-7.

Developmentally regulated alternative splicing of brain myelin-associated glycoprotein mRNA is lacking in the quaking mouse.

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1
Department of Neurology, Niigata University, Japan.

Abstract

Evidence is presented that expression of the two myelin-associated glycoprotein mRNAs is developmentally regulated in mouse brain. In quaking mouse, the mRNA without a 45-nucleotide exon portion was scarcely expressed throughout development. We conclude that the mechanism of splicing out the 45-nucleotide exon portion is lacking in quaking mouse.

PMID:
2454205
DOI:
10.1016/0014-5793(88)80762-2
[Indexed for MEDLINE]
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