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Science. 2014 Feb 14;343(6172):747-751. doi: 10.1126/science.1243518.

A genetic atlas of human admixture history.

Author information

1
UCL Genetics Institute, University College London, Gower Street, London WC1E 6BT, UK.
2
Department of Zoology, Oxford University, South Parks Road, Oxford OX1 3PS, UK.
3
Wellcome Trust Centre for Human Genetics, Oxford University, Roosevelt Drive, Oxford OX3 7BN, UK.
4
Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK.
5
Max Planck Institute for Evolutionary Anthropology, DeutscherPlatz 6, 04103 Leipzig, Germany.
6
Department of Statistics, Oxford University, 1 South Parks Road, Oxford OX1 3TG, UK.
#
Contributed equally

Abstract

Modern genetic data combined with appropriate statistical methods have the potential to contribute substantially to our understanding of human history. We have developed an approach that exploits the genomic structure of admixed populations to date and characterize historical mixture events at fine scales. We used this to produce an atlas of worldwide human admixture history, constructed by using genetic data alone and encompassing over 100 events occurring over the past 4000 years. We identified events whose dates and participants suggest they describe genetic impacts of the Mongol empire, Arab slave trade, Bantu expansion, first millennium CE migrations in Eastern Europe, and European colonialism, as well as unrecorded events, revealing admixture to be an almost universal force shaping human populations.

PMID:
24531965
PMCID:
PMC4209567
DOI:
10.1126/science.1243518
[Indexed for MEDLINE]
Free PMC Article
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