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Curr Opin Cell Biol. 2014 Feb;26:113-22. doi: 10.1016/j.ceb.2013.12.005. Epub 2014 Jan 7.

Linked in: formation and regulation of microtubule attachments during chromosome segregation.

Author information

1
Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA. Electronic address: dcheerambathur@ucsd.edu.
2
Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA. Electronic address: abdesai@ucsd.edu.

Abstract

Accurate segregation of the replicated genome during cell division depends on dynamic attachments formed between chromosomes and the microtubule polymers of the spindle. Here we review recent advances in mechanistic analysis of microtubule attachment formation and regulation.

PMID:
24529253
PMCID:
PMC3940152
DOI:
10.1016/j.ceb.2013.12.005
[Indexed for MEDLINE]
Free PMC Article

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