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Clin Neuropsychol. 2014;28(2):252-68. doi: 10.1080/13854046.2013.875595. Epub 2014 Feb 13.

Cognition in MCI and Alzheimer's disease: baseline data from a longitudinal study of the NTB.

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1
a Metis Cognition Ltd ., Wiltshire , UK.

Abstract

Baseline data are summarized from a study examining the psychometric properties of the Neuropsychological Test Battery (NTB) and its subtests, and correlating the NTB with other cognitive and functional assessments. A multicenter, longitudinal, non-interventional study included mild to moderate Alzheimer's disease (AD, n = 196), mild cognitive impairment (MCI, n = 70), or normal cognition participants (NC, n = 75). The NTB, other cognitive assessment tools, functional/behavioral questionnaires, and health outcome assessments were administered. At baseline composite NTB, NTB memory, and NTB executive function z-scores were significantly lower for participants with AD compared with MCI, and for participants with MCI compared with NC. The composite NTB z-score had high test-retest reliability between screening and baseline. The results of this study suggest that NTB exhibits good reliability in patients with mild to moderate AD and MCI.

PMID:
24521259
DOI:
10.1080/13854046.2013.875595
[Indexed for MEDLINE]

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