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Restor Dent Endod. 2014 Feb;39(1):1-6. doi: 10.5395/rde.2014.39.1.1. Epub 2014 Jan 20.

Platelet rich fibrin - a novel acumen into regenerative endodontic therapy.

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Department of Pedodontics and Preventive Dentistry, Sharad Pawar Dental College, Sawangi(M), Wardha, Maharashtra, India.
Department of Orthodontics and Dentofacial Orthopaedics, Sharad Pawar Dental College, Sawangi(M), Wardha, Maharashtra, India.


Research into regenerative dentistry has added impetus onto the field of molecular biology. It can be documented as a prototype shift in the therapeutic armamentarium for dental disease. Regenerative endodontic procedures are widely being added to the current armamentarium of pulp therapy procedures. The regenerative potential of platelets has been deliberated. A new family of platelet concentrates called the platelet rich fibrin (PRF) has been recently used by several investigators and has shown application in diverse disciplines of dentistry. This paper is intended to add light on the various prospects of PRF and clinical insights to regenerative endodontic therapy.


Platelet rich fibrin; Regenerative endodontics; Scaffold

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