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PLoS One. 2014 Feb 4;9(2):e87884. doi: 10.1371/journal.pone.0087884. eCollection 2014.

Risk factors for cerebrovascular disease mortality among the elderly in Beijing: a competing risk analysis.

Author information

1
Beijing Geriatric Healthcare Center, Xuan Wu Hospital, Capital Medical University, Beijing, China.
2
School of Public Health, Capital Medical University, Beijing, China ; Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.
3
Division of Epidemiology and Biostatistics, Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, United States of America ; Center for Clinical and Translational Science and Training, University of Cincinnati, Cincinnati, Ohio, United States of America.
4
Institute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control, Beijing, China.
5
School of Medical Science, Edith Cowan University, Perth, Australia.
6
School of Public Health, Capital Medical University, Beijing, China ; Beijing Municipal Science and Technology Commission, Beijing, China.
7
School of Public Health, Capital Medical University, Beijing, China ; Epidemiology and Public Health, University College Cork, Cork, Ireland.

Abstract

OBJECTIVE:

To examine the associations of combined lifestyle factors and physical conditions with cerebrovascular diseases (CBVD) mortality, after accounting for competing risk events, including death from cardiovascular diseases, cancers and other diseases.

METHODS:

Data on 2010 subjects aged over 55 years were finally analyzed using competing risk models. All the subjects were interviewed by the Beijing Longitudinal Study of Aging (BLSA), in China, between 1 January 1992 and 30 August 2009.

RESULTS:

Elderly females were at a lower risk of death from CBVD than elderly males (HR = 0.639, 95% CI = 0.457-0.895). Increasing age (HR = 1.543, 95% CI = 1.013-2.349), poor self-rated health (HR = 1.652, 95% CI = 1.198-2.277), hypertension (HR = 2.201, 95% CI = 1.524-3.178) and overweight (HR = 1.473, 95% CI = 1.013-2.142) or obesity (HR = 1.711, 95% CI = 1.1754-2.490) was associated with higher CBVD mortality risk. Normal cognition function (HR = 0.650, 95% CI = 0.434-0.973) and living in urban (HR = 0.456, 95% CI = 0.286-0.727) was associated with lower CBVD mortality risk. Gray's test also confirmed the cumulative incidence (CIF) of CBVD was lower in the 'married' group than those without spouse, and the mortality was lowest in the 'nutrition sufficient' group among the 'frequent consumption of meat group' and the 'medial type group' (P value<0.001).

CONCLUSIONS:

CBVD mortality was associated with gender, age, blood pressure, residence, BMI, cognitive function, nutrition and the result of self-rated health assessment in the elderly in Beijing, China.

PMID:
24504327
PMCID:
PMC3913670
DOI:
10.1371/journal.pone.0087884
[Indexed for MEDLINE]
Free PMC Article
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