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Clin Radiol. 2014 Apr;69(4):e183-9. doi: 10.1016/j.crad.2013.12.001. Epub 2014 Feb 4.

CT angiography of the neck: value of contrast medium dose reduction with low tube voltage and high tube current in a 64-detector row CT.

Author information

1
Clinical Medical College, Yangzhou University, Radiology Department, Subei People's Hospital of Jiangsu Province, Yangzhou, China.
2
Clinical Medical College, Yangzhou University, Radiology Department, Subei People's Hospital of Jiangsu Province, Yangzhou, China. Electronic address: wujingtao5688@163.com.
3
Radiology Department, Huashan Hospital, Fudan University, Shanghai, China.

Abstract

AIM:

To evaluate the feasibility of a low-dose contrast medium protocol for 64-detector row computed tomography angiography (CTA) of the neck using a low-tube-voltage/high-tube-current setting.

MATERIALS AND METHODS:

A phantom study was performed using 64-detector row spiral CT at multiple tube voltage and current settings. Iodine contrast medium attenuation curves were acquired by processing and used to select the best contrast medium-to-noise ratio (CNR). A prospective clinical study was then performed on 84 patients requiring neck CTA. Patients were randomly divided into two groups of 42. Group A was examined using the conventional imaging protocol (120 kV, 400 mAs) and group B was examined at 80 kV and 600 mAs along with a 50% reduction in contrast medium dose. The CT dose index-volume (CTDI(vol)), background noise (BN), and CNR were measured and statistically analysed. Various image quality criteria were evaluated by two senior radiologists using a qualitative five-point scale.

RESULTS:

Comparing group B with A, CTDIvol decreased by 54% (B: 27.48 mGy, A: 59.11 mGy), however, the CNR increased by 50%. The mean attenuation, which was caused by venous streak artefacts, was significantly lower in group B than A. Qualitative image analysis found that all criteria were significantly better for group B than A.

CONCLUSION:

At 64-detector row spiral CT, the low-tube-voltage/high-tube-current with low-dose contrast medium protocol was superior to the conventional protocol regarding radiation dose, venous streak artefacts, and image quality, and is feasible for CTA of the neck.

PMID:
24503560
DOI:
10.1016/j.crad.2013.12.001
[Indexed for MEDLINE]

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