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Curr Pain Headache Rep. 2014 Mar;18(3):402. doi: 10.1007/s11916-013-0402-3.

Migraine and epilepsy in the pediatric population.

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Departments of Neurology and Pediatrics, Johns Hopkins University School of Medicine, 200 North Wolfe Street, Suite 2158, Baltimore, MD, 21287, USA,


Individually, childhood epilepsy and migraine are two of the most common conditions seen in pediatric neurology. What complicates matters is that there can be marked similarities between migraine and epilepsy as well as a variety of underlying conditions that predispose children to both seizures and headache. Thus, separating epilepsy from migraine may not be easy, but can be done with a detailed history as well as timely use of ancillary testing. Once children have been diagnosed with epilepsy, migraine, or both, treatment options become essential in attempts to manage these common, yet often disabling, neurological conditions. Acute interventions tend to be condition specific while preventative options may overlap for migraine and epilepsy. In the following review, we will discuss the epidemiology of childhood epilepsy and headache, the association between them, as well as how to differentiate epilepsy from migraine. Treatment strategies will follow before concluding with a discussion on prognosis.

[Indexed for MEDLINE]

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